5.7/10
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389 user 376 critic

Splice (2009)

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1:24 | Trailer
Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.

Director:

Vincenzo Natali

Writers:

Vincenzo Natali (screenplay), Antoinette Terry Bryant (screenplay) | 3 more credits »
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Popularity
2,203 ( 984)
4 wins & 23 nominations. See more awards »

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Cast

Complete credited cast:
Adrien Brody ... Clive Nicoli
Sarah Polley ... Elsa Kast
Delphine Chanéac ... Dren (as Delphine Chaneac)
Brandon McGibbon ... Gavin Nicoli
Simona Maicanescu ... Joan Chorot
David Hewlett ... William Barlow
Abigail Chu ... Child Dren
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Storyline

Two young rebellious scientists are told by their employers to halt groundbreaking work that has seen them produce new creatures with medical benefits by splicing together multiple organisms' DNA. They decide to secretly continue their work, but this time splicing in human DNA. Written by Anonymous

Plot Summary | Plot Synopsis

Taglines:

She's Not Human ... Not Entirely. See more »

Genres:

Drama | Horror | Sci-Fi

Motion Picture Rating (MPAA)

Rated R for disturbing elements including strong sexuality, nudity, sci-fi violence and language | See all certifications »

Parents Guide:

View content advisory »
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Details

Country:

Canada | France | USA

Language:

English | French

Release Date:

4 June 2010 (USA) See more »

Also Known As:

Splice See more »

Filming Locations:

Ontario, Canada See more »

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Box Office

Budget:

$30,000,000 (estimated)

Opening Weekend USA:

$7,385,277, 6 June 2010

Gross USA:

$17,010,170

Cumulative Worldwide Gross:

$27,127,620
See more on IMDbPro »

Company Credits

Show more on IMDbPro »

Technical Specs

Runtime:

Sound Mix:

SDDS | DTS | Dolby Digital

Color:

Color

Aspect Ratio:

1.85 : 1
See full technical specs »
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Did You Know?

Trivia

The movements of baby Dren was based on visual effects supervisor Bob Munroe's Golden Retriever dog. Munroe states, "I was out one night walking my Golden Retriever and when he tore across the field, I noticed that as fast as those legs were going, his head and tail stayed perfectly still. I took that to the studio and made that work with baby Dren." See more »

Goofs

When Ginger and Fred meet in the case at the shareholders' meeting, they began to hiss and protract their claws and fangs. From behind, Ginger's fang is already out, and Fred begins to push his out. In the next shot, Ginger pushes her fang out for the first time. See more »

Quotes

CEO: No more monsters!
See more »

Crazy Credits

The company logos appear on X-rays. See more »

Alternate Versions

Finnish and German Blu-rays are 108 min. versions. US and UK versions 104 min. See more »

Connections

Referenced in Honest Trailers: The Oscars 2018 (2018) See more »

Soundtracks

Zeppelin Interpolation
Written and Performed by Bob Wiseman
Courtesy of The Artist
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Frequently Asked Questions

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User Reviews

 
A likable but flawed sci-fi tale
4 March 2010 | by derekrankineSee all my reviews

Splice centres on two renowned young scientists (Adrien Brody and Sarah Polley) that are quasi-famous for successfully creating a new species of animal, a species with enormous pharmaceutical industry potential in the form of an ability to secrete profitable proteins. Despite a refusal by their company bosses to approve the next stage of the project, or anything that tampers with human DNA, their ambitions lead them to create a human-animal hybrid by combining human genes with those of the created species. This in turn leads to the creation of a new entity they name Dren, which they raise and attempt to study as a personal project concealed from their employers and colleagues.

The story becomes highly engrossing as we follow the creature's development alongside that of the two scientists, who are in a relationship that becomes increasingly strained by a series of ethical and logistical dilemmas. The two central performances are well-judged, but the real star is Dren; or the CGI responsible for her creation, which is always convincing and solid at all stages of the creature's evolution. Vincenzo Natali's visually intense direction is also worth mentioning, and he clearly enjoys playing with a generous budget as compared with his previous features like Cube.

This is, however, no modern masterpiece – the plot becomes predictable and contrived in the final third, the minor characters are little more than stereotypes (lax young brother, venal bosses) and the comedic elements of the film don't always sit comfortably with the horror aspects (there is, however, a notable exception in a hilarious scene towards the end). But these drawbacks are outweighed by the plus points, which makes Splice an enjoyable experience overall.


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