A psychiatrist who is married, is having an affair. His wife threatens to divorce him and take him to the cleaners if she ever catches him. So along with his mistress he plans to kill her and make it seem like she was killed by an intruder. He goes out of town as part of his plan and returns to find the police there investigating and the man investigating is Lt. Columbo. Columbo is a little odd and he asks the man some questions that he finds intrusive. Columbo continues to question him and the man's friend an ADA warns Columbo to watch his step. But Columbo goes on.
The pilot episode of television's most popular detective.
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Did You Know?
Unlike in the regular show where Lieutenant Columbo had a more subtle, incisive method of interrogation, in "Prescription: Murder" he is more aggressive and intimidating. See more
During the "session" with Columbo, the doctor is gesturing with his drink. Toward the end of talking about his hypothetical murderer, he slops his drink a couple times, but ignores it and carries on. This is a natural action for someone who is gesturing during a conversation that he is engrossed in. See more
Dr. Ray Flemming
You're an intelligent man, Columbo, but you hide it.
The beginning credits feature a series of brightly colored animated splotches. The splotches were meant to resemble the ink blots used in a Rorschach test, as the villain in this movie was a psychiatrist. See more
Referenced in Columbo: Murder by the Book